Phospho eif4b
WebPhospho-eIF4E (Ser209) Antibody detects endogenous levels of eIF4E only when phosphorylated at serine 209. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser209 of human eIF4E. WebJun 8, 2006 · eIF4B Ser422 phosphorylation persists in cells lacking S6K1 and S6K2 To further corroborate the existence of an eIF4B kinase that is distinct from S6K in cells …
Phospho eif4b
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WebJan 25, 2024 · We hypothesised that the effect of SLC25A11 knockdown on inhibiting protein translation was mediated by the inactivation of translational elongation factors such as eIF4B through the depletion of the ATP supply, which resulted in a critical reduction of p-eIF4B dependent synthesis of proteins including c-Myc in cancer cells (Fig. 4 b). WebApr 6, 2024 · The protein expression of mTOR, phospho-mTOR, p70 S6 kinase (p70 S6K), phospho-p70 S6K, eIF4B, phospho-eIF4B, eIF4G, 4E-BP1, phospho-4E-BP1, eIF4E, phospho-eIF4E, and Rpb1 in the liver was assessed using western blotting. Actin was used as the loading control. (Specific antibody information is provided in the Supplementary Materials.)
WebPhospho-EIF4B (Ser406) EIF4B (Eukaryotic Translation Initiation Factor 4B) is a Protein Coding gene. Among its related pathways are Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include nucleic acid binding ... WebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins are EIF4A, EIF4F. eIF4B is involved in translation of numerous proliferative or anti-apoptotic mRNAs with highly structured 5'UTR and subsequently affect cell growth …
WebAll lanes : Anti-eIF4B (phospho S504) antibody [EP2261Y] (ab75823) at 1/50000 dilution Lane 1 : 293T cell lysate, untreated Lane 2 : 293T cell lysate, treated with AP … Web酶联生物为您提供大鼠热休克蛋白β6(hspβ6)检测试剂盒的参数及2024年最新报价，厂家专业的大鼠热休克蛋白β6(hspβ6)检测试剂盒售后服务团队，是您值得信赖的合作伙伴
WebJun 8, 2024 · The phosphorylation of eIF2α occurs on serine 51 in response to the activation of one out of four eIF2α kinases 4, 5, 6. EIF2AK1, commonly known as heme-regulated inhibitor (HRI), is activated by...
WebInvitrogen Anti-Phospho-EIF4B (Ser504) Polyclonal, Catalog # PA5-114571. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and Immunohistochemistry (PFA fixed) … porsche dealers seattle areaWebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins … porsche dealers south africaWebAug 4, 2024 · Phosphorylated eIF4B levels are normalized against total eIF4B, then for loading (Tubulin) and shown as fold change over control (untreated neurons). Data are … iris of hattiesburg clinicWebJan 5, 2024 · The translation initiation factor eIF4A is a member of the “DEAD box” family of helicases that catalyze the ATP-dependent unwinding of RNA duplexes and facilitates 43S ribosome complex scanning through highly structured regions of the 5′-untranslated region (UTR) and recognition of the AUG initiation codon. porsche dealers of southern calWebThe eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. iris of cameraWebAug 17, 2014 · Phospho-proteomics identified the mTOR pathway to be of interest in EGFR inhibitor resistance. In our studies, combining gefitinib and temsirolimus decreased cell growth and survival in a synergistic manner. Our data identified eIF4B, as a potentially key fragile point in EGFR and mTOR inhibitor synergy. iris of helheimWebRecombinant Anti-eIF4B (phospho S406) antibody [EPR7683] - BSA and Azide free (ab248698) Datasheet Certificate of Compliance Submit a review Submit a question Product price, shipping and contact information Currently … porsche dealers suffolk